Marom Bikson, PhD
Education
Research Fellow, Neurophysiology Unit, University of Birmingham Medical School, U.K., 2003
Ph.D., Biomedical Engineering, Case Western Reserve University Cleveland, OH, 2000
B.S., Biomedical Engineering (EE Concentration), Johns Hopkins University, Baltimore, MD, 1995
Research Areas and Expertise
Prof. Marom Bikson’s research group studies the effects of electricity on the human body and applies this knowledge toward the development of medical devices and electrical safety guidelines.
“Our goal is to improve human health by combining engineering innovation, with cutting-edge experimental techniques, and original bio-medical insight. This challenge requires creative problem-solving, precision, and imagination. We are tremendously fortunate to access the extensive resources of the City University of New York research centers and of the New York Center for Biomedical Engineering hospital network.”
Specific areas of research include:
Medical devices including biosensors, drug delivery technology, and electrotherapy devices for neurological disorders.
Medical device safety including electrical hazards, electroporation, heating damage, and safe stimulation protocols.
Electrical safety, electric shock hazards, and accidental electrocution.
Understanding the neuronal networks underlying normal brain function, including the role of endogenous electric fields.
Developing new treatments for neurological diseases including epilepsy and depression, through translational research.
Prof. Bikson’s group uses a range of research and engineering design tools including cellular and animal studies, computer simulations, imaging, and clinical evaluation. Prof. Bikson’s research has received support from funding agencies including NIH (NINDS,NCI,NIGMS, NIMH), DoD (AFRL), The Andy Grove Foundation, The Wallace H. Coulter Foundation, The Epilepsy Foundation, and the Howard Hughes Medical Institute. Prof. Bikson is co-founder and CEO of Soterix Medical Inc.
Prof. Bikson is actively involved in biomedical education including outreach to underserved groups. Prof. Bikson is founding chairman of Neuromodec and its events including the NYCmeuromodulation conference and the Neuromodec tDCS Workshop.
Prof. Bikson has provided extensive technical support and consulting for biomedical companies (Medtronic, Boston Scientific, NuSkin, Nevrocorp, Ion Channel Innovations, Wyle, Thync), utility companies (Con Edison, First Energy), government agencies (NIH, DoD, NASA, NY State Public Service Commission, Potomac Institute for Policy Studies), and litigation support.
View Prof. Bikson’s CV: PDF
Prof. Bikson is co-director of Neural Engineering at The City College of New York and the New York Center for Biomedical Engineering. More project information at CCNY Neural Engineering.
Selected Publications
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2020
Shin DW, Fan J, Luu E, Khalid W, Xia Y, Khadka N, Bikson M, Fu BM. In Vivo Modulation of the Blood–Brain Barrier Permeability by Transcranial Direct Current Stimulation (tDCS). Annals of Biomedical Engineering 2020. https://doi.org/10.1007/s10439-020-02447-7. PDF
Borges H, Dufau A, Paneri B, Woods AJ, Knotkova H, Bikson M. Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation. Journal of Visualized Experiments 2020. https://doi.org/10.3791/59204. PDF
2019
Bikson M, Dmochowski J. What it means to go deep with non-invasive brain stimulation. Clinical Neurophysiology. 2019 Dec. http://dx.doi.org/10.1016/j.clinph.2019.12.003. In Press.
Esmaeilpour Z, Shereen AD, Ghobadi‐Azbari P, Datta A, Woods AJ, Ironside M, O’Shea J, Kirk U, Bikson M, Ekhtiari H. Methodology for tDCS integration with fMRI. Human Brain Mapping. 2019 Dec 24. http://dx.doi.org/10.1002/hbm.24908. PDF
Koganemaru S, Mikami Y, Matsuhashi M, Truong DQ, Bikson M, Kansaku K, Mima T. Cerebellar transcranial alternating current stimulation modulates human gait rhythm. Neuroscience Research. 2019 Dec. http://dx.doi.org/10.1016/j.neures.2019.12.003. PDF
Khadka N, Bikson M. Response to the Letter to the Editor by Caraway et al. on “Tissue Temperature Increases by a 10 kHz Spinal Cord Stimulation System: Phantom and Bioheat Model”. Neuromodulation. 2019. https://doi.org/10.1111/ner.13079. PDF
Khadka N, Liu X, Zander H, Swami J, Rogers E, Lempka SF, Bikson M. Realistic Anatomically Detailed Open-Source Spinal Cord Stimulation (RADO-SCS) Model. bioRxiv. 2019. https://doi.org/10.1101/857946. PDF
Sivaramakrishnan A, Datta A, Bikson M, Madhavan S. Remotely supervised transcranial direct current stimulation: A feasibility study for amyotrophic lateral sclerosis. NeuroRehabilitation. 2019 Dec 16;45(3):369–78. http://doi.org/10.3233/NRE-192851. In Press.
Morya E, Monte-Silva K, Bikson M, Esmaeilpour Z, Biazoli CE, Fonseca A, Bocci T, Farzan F, Chatterjee R, Hausdorff JM, da Silva Machado DG, Russowsky Brunoni A, Mezger E, Aparecida Mascaleski L, Pegado R, Sato JR, Caetano MS, Nunes Sá K, Tanaka C, Li LM, Fontes Baptista A, Hideki Okano A. Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes. Journal of NeuroEngineering and Rehabilitation. 2019 Nov 15;16(1). http://dx.doi.org/10.1186/s12984-019-0581-1. PDF
Lazarev VV, Gebodh N, Tamborino T, Bikson M, Caparelli-Daquer EM. Experimental-design Specific Changes in Spontaneous EEG and During Intermittent Photic Stimulation by High Definition Transcranial Direct Current Stimulation. Neuroscience 2020;426:50–8. https://doi.org/10.1016/j.neuroscience.2019.11.016. PDF
Jiang J, Truong DQ, Esmaeilpour Z, Huang Y, Badran BW, Bikson M. Enhanced tES and tDCS computational models by meninges emulation. Journal of Neural Engineering. 2019 Nov 5; http://dx.doi.org/10.1088/1741-2552/ab549d. In Press.
Argyelan M, Oltedal L, Deng Z-D, Wade B, Bikson M, Joanlanne A, Sanghani S, Bartsch H, Cano M, Dale AM, Dannlowski U, Dols A, Enneking V, Espinoza R, Kessler U, Narr KL, Oedegaard KJ, Oudega ML, Redlich R, Stek ML, Takamiya A, Emsell L, Bouckaert F, Sienaert P, Pujol J, Tendolkar I, van Eijndhoven P, Petrides G, Malhotra AK, Abbott C. Electric field causes volumetric changes in the human brain. eLife. 2019 Oct 23;8. Available from: http://dx.doi.org/10.7554/eLife.49115
Kronberg G, Rahman A, Sharma M, Bikson M, Parra LC. Direct current stimulation boosts hebbian plasticity in vitro. Brain Stimulation. 2019 Oct; http://dx.doi.org/10.1016/j.brs.2019.10.014. PDF
Khadka N, Truong D, Williams P, MArtin J, Bikson M. The Quasi-uniform assumption for Spinal Cord Stimulation translational research. Journal of Neuroscience Methods. 2019. https://doi.org/10.1016/j.jneumeth.2019.108446. PDF
Bahr Hosseini M, Hou J, Bikson M, Iacoboni M, Gornbein J, Saver JL. Central Nervous System Electrical Stimulation for Neuroprotection in Acute Cerebral Ischemia. Stroke. 2019 Oct;50(10):2892–901. https://doi.org/10.1161/STROKEAHA.119.025364. PDF
Khadka N, Borges H, Paneri B, Kaufman T, Nassis E, Zannou AL, Shin Y, Choi H, Kim S, Lee K, Bikson M. Adaptive current tDCS up to 4 mA. Brain Stimulation. 2019 Jan;13(1):69–79. https://doi.org/10.1016/j.brs.2019.07.027. PDF
Bikson M, Esmaeilpour Z, Adair D, Kronberg G, Tyler WJ, Antal A, Datta A, Sabel BA, Nitsche MA, Loo C, Edwards D, Ekhtiari H, Knotkova H, Woods AJ, Hampstead BM, Badran BW, Peterchev AV. (2019). Transcranial electrical stimulation nomenclature. Brain Stimulation. https://doi.org/10.1016/j.brs.2019.07.010 PDF
Seibt O, Truong D, Khadka N, Huang Y, Bikson M. Computational Finite Element Method (FEM) forward modeling workflow for transcranial Direct Current Stimulation (tDCS) current flow on MRI-derived head: Simpleware and COMSOL Multiphysics tutorial. bioRxiv 704940. 2019 July 16; https://doi.org/10.1101/704940 PDF
Valero-Cabré A, Sanches C, Godard J, Fracchia O, Dubois B, Levy R, Truong DQ, Bikson M, Teichmann M. (2019). Language boosting by transcranial stimulation in progressive supranuclear palsy. Neurology, https://doi.org/10.1212/wnl.0000000000007893. PDF
Ekhtiari H, Tavakoli H, Addolorato G, Baeken C, Bonci A, Campanella S, Castelo-Branco L, Challet-Bouju G, Clark VP, Claus E, Dannon PN, Del Felice A, den Uyl T, Diana M, di Giannantonio M, Fedota JR, Fitzgerald P, Gallimberti L, Grall-Bronnec M, Herremans SC, Herrmann MJ, Jamil A, Khedr E, Kouimtsidis C, Kozak K, Krupitsky E, Lamm C, Lechner WV, Madeo G, Malmir N, Martinotti G, McDonald W, Montemitro C, Nakamura-Palacios EM, Nasehi M, Noël X, Nosratabadi M, Paulus M, Pettorruso M, Pradhan B, Praharaj SK, Rafferty H, Sahlem G, Salmeron BJ, Sauvaget A, Schluter RS, Sergiou C, Shahbabaie A, Sheffer C, Spagnolo PA, Steele VR, Yuan T-F, van Dongen J, Van Waes V, Venkatasubramanian G, VerdejoGarcía A, Verveer I, Welsh J, Wesley MJ, Witkiewitz K, Yavari F, Zarrindast M-R, Zawertailo L, Zhang X, Cha Y-H, George TP, Frohlich F, Goudriaan AE, Fecteau S, Daughters SB, Stein EA, Fregni F, Nitsche MA, Zangen A, Bikson M, Hanlon CA (2019). Transcranial Electrical and Magnetic Stimulation (tES and TMS) for Addiction Medicine: A consensus paper on the present state of the science and the road ahead. Neuroscience & Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2019.06.007. In Press.
Im JJ, Jeong H, Bikson M, Woods AJ, Unal G, Oh JK, Na S, Park, J-S, Knotkova H, Song I-K, Chung Y-A. Effects of 6-month at-home transcranial direct current stimulation on cognition and cerebral glucose metabolism in Alzheimer’s disease. Brain Stimulation. 2019. https://doi.org/10.1016/j.brs.2019.06.003. PDF
Meiron O, Gale R, Namestnic J, Bennet-Back O, Gebodh N, Esmaeilpour Z, Mandzhiyev V, Bikson M. Antiepileptic Effects of a Novel Non-invasive Neuromodulation Treatment in a Subject With Early-Onset Epileptic Encephalopathy: Case Report With 20 Sessions of HD-tDCS Intervention. Front. Neurosci. 13:547. 2019. https://doi:org/10.3389/fnins.2019.00547. PDF
Ambrose-Zaken GV, FallahRad M, Bernstein H, Wall Emerson R, Bikson M. Wearable Cane and App System for Improving Mobility in Toddlers/Pre-schoolers With Visual Impairment. Front. Educ. 4:44. 2019. https://doi.org/10.3389/feduc.2019.00044. PDF
Zannou AL, Khadka N, Truong D, FallahRad M, Kopell B, Bikson, M. Tissue Temperature Increases by a 10 kHz Spinal Cord Stimulation System: Phantom and Bioheat Model. Neuromodulation. 2019. https://doi.org/10.1111/ner.12980. PDF
Huang Y, Datta A, Bikson M, Parra LC. Realistic vOlumetric-Approach to Simulate Transcranial Electric Stimulation — ROAST — a fully automated open-source pipeline. Journal of Neural Engineering. 2019 https://doi.org/10.1088/1741-2552/ab208d. In Press
FallahRad M, Zannou AL, Khadka N, Prescott SA, Ratte S, Zhang T, Esteller R, Hershey B, Bikson M. Topical Review: Electrophysiology equipment for reliable study of kHz electrical stimulation. The Journal of Physiology. 2019. https://doi.org/10.1113/JP277654. PDF
Lattari E, Vieira LAF, Oliveira BRR, Unal G, Bikson M, de Mello Pedreiro RC, Marques Neto SR, Machado S, Maranhão-Neto GA. Effects of Transcranial Direct Current Stimulation With Caffeine Intake on Muscular Strength and Perceived Exertion. Journal of Strength and Conditioning Research, 2019. https://doi.org/10.1519/jsc.0000000000003123. PDF
Hadar R, Winter R, Edemann-Callesen H, Wieske F, Habelt B, Khadka N, Felgel V, Barroeta Hlusicka E, Reis J, Alexandru Tatarau C, Funke K, Fritsch B, Bernhardt N, Bikson M, Nitsche MA, Winter C. Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats. Nature Molecular Psychiatry. 2019. https://doi.org/10.1038/s41380-019-0356-x. PDF
Khadka N., Woods A.J., Bikson M. (2019) Transcranial Direct Current Stimulation Electrodes. In: Knotkova H., Nitsche M., Bikson M., Woods A. (eds) Practical Guide to Transcranial Direct Current Stimulation. Springer, Cham. https://doi.org/10.1007/978-3-319-95948-1_10. PDF
Fonteneau C, Mondino M, Arns M, Baeken C, Bikson M, Brunoni AR, Burke MJ, Neuvonen T, Padberg F, Pascual-Leone A, Poulet E, Ruffini G, Santarnecchi E, Sauvaget A, Schellhorn K, Suaud-Chagny M-F, Palm U, Brunelin J. Sham tDCS: a hidden source of variability? Reflections for further blinded, controlled trials. Brain Stimulation. https://doi.org/10.1016/j.brs.2018.12.977. 2019. PDF
2018
Badran BW, Yu AB, Adair D, Mappin G, DeVries WH, Jenkins DD, George MS, Bikson M. Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Technique, Targeting, and Considerations. J. Vis. Exp. (), e58984, doi:10.3791/58984 (2018). PDF
da S Machado DG, Unal G, Andrade SM, Moreira A, Altimari LR, Brunoni AR, Perrey S, Mauger AR, Bikson M, Okano AH. (2018). Effect of transcranial direct current stimulation on exercise performance: A systematic review and meta-analysis. Brain Stimulation. 12(3), 593–605. https://doi.org/10.1016/j.brs.2018.12.227. PDF
Dobbs B., Pawlak N., Biagioni M., Agarwal S., Shaw M., Pilloni G., Bikson M., Datta A., Charvet L. (2018). Generalizing remotely supervised transcranial direct current stimulation (tDCS): feasibility and benefit in Parkinson’s disease. Journal of NeuroEngineering and Rehabilitation, 15(1). https://doi.org/10.1186/s12984-018-0457-9. PDF
Marron EM, Viejo-Sobera R, Cuatrecasas G, Redolar D, García-Lorda P, Datta A, Bikson M, Magerowski G, Alonso-Alonso M. Prefronto-cerebellar neuromodulation affects appetite in obesity. 2018; Int J Obesity. doi: 10.1038/s41366-018-0278-8. PDF
Lee SH, Im JJ, Oh JK, Choi EK, Yoon S, Bikson M, Song I-U, Jeong H, Chung Y-A (2018). Transcranial direct current stimulation for online gamers: A prospective single-arm feasibility study. Journal of Behavioral Addictions, 1–5. Akademiai Kiado Zrt, doi: 10.1556/2006.7.2018.107. PDF
Gebodh N, Esmaeilpour Z, Adair D, Chelette K, Dmochowski J, Woods AJ, Kappenman ES, Parra LC, Bikson M. Inherent physiological artifacts in EEG during tDCS. NeuroImage. (185). pp. 408-424. 15 January 2019, doi: 10.1016/j.neuroimage.2018.10.025. PDF
Badran BW, Yu AB, Adair DKP, Mappin G, DeVries WH, Jenkins DD, George MS, Bikson M. Methodological Description of the Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Humans: Technique, Targeting and Considerations. J Vis Exp. 2018. In Press.
Silva-Filho E, Okano AH, Morya E, Albuquerque J, Cacho E, Unal G, Bikson M, Pegado R. Neuromodulation treats Chikungunya arthralgia: a randomized controlled trial. Sci. Rep. 8:16010. 2018 October 30, doi: 10.1038/s41598-018-34514-4. PDF
Santos TEG, Favoretto FB, Toostani IG, Nascimento DC, Rimoli BP, Bergonzoni E, Lemos TW, Truong DQ, Delbem ACB, Makkiabadi B, Moraes R, Louzada F, Bikson M, Leite JP, Edwards DJ. Manipulation of Human Verticality Using High-Definition Transcranial Direct Current Stimulation. Front. Neurol. 2018 October 22, doi: 10.3389/fneur.2018.00825. PDF
Zannou AL*, Khadka N*, Truong DQ, Zhang T, Esteller R, Hershey B, Bikson M. Temperature Increases by kilohertz frequency Spinal Cord Stimulation. Brain Stimulation. 2018. doi: 10.1016/j.brs.2018.10.007. PDF
Truong DQ, Bikson M. Physics of Transcranial Direct Current Stimulation Devices and Their History. The Journal of ECT. 34(3), pp. 137–143. 2018 September 01, doi: 10.1097/yct.0000000000000531. PDF
Khadka N, Borges H, Zannou AL, Jang J, Kim B, Lee K, Bikson M. Dry tDCS: Tolerability of a novel multilayer hydrogel composite non-adhesive electrode for transcranial direct current stimulation. Brain Stim. 11(5), pp. 1044-1053. 2018 September-October, doi: 10.1016/j.brs.2018.07.049. PDF
Badran BW, Jenkins DD, Devries WH, Dancy M, Summers PM, Mappin GM, Bernstein H, Bikson M, Cocker-Bolt P, George MS. Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Improving Oromotor Function in Newborns. Brain Stim. 2018 June 30, doi: 10.1016/j.brs.2018.06.009. PDF
Cancel LM, Arias, K, Bikson M, Tarbell JM. Direct current stimulation of endothelial monolayers induces a transient and reversible increase in transport due to the electroosmotic effect. Sci Rep. 2018 June 18. 8:9265 doi: 10.1038/s41598-018-27524-9. PDF
Badran BW, Brown JC, Dowdle LT, Mithoefer OJ, LaBate NT, Coatsworth J, DeVreis WH, Austelle CW, McTeague LM, Yu A, Bikson M, Jenkins DD, George MS. Tragus or cymba conchae? Investigating the anatomical foundation of transcutaneous auricular vagus nerve stimulation (taVNS). Brain Stim. 2018 June 06, doi: 10.1016/j.brs.2018.06.003. PDF
Huh Y, Jung D, Seo T, Sun S, Kim SH, Rhim H, Chung S, Kim C, Kwon Y, Bikson M, Chung Y, Kim JJ, Cho J. Brain stimulation patterns emulating endogenous thalamocortical input to parvalbumin-expressing interneurons reduce nociception in mice. Brain Stim. 2018 May 09, doi: 10.1016/j.brs.2018.05.007. PDF
Reckow J, Rahman-Filipiak A, Garcia S, Schlaefflin S, Calhoun O, DaSilva AF, Bikson M, Hampstead BM. Tolerability and blinding of 4×1 High-Definition transcranial direct current stimulation (HD-tDCS) at two and three milliamps. Brain Stim. 2018 May 04, doi: 10.1016/j.brs.2018.04.022. PDF
Knotkova H, Riggs A, Berisha D, Borges H, Bernstein H, Patel V, Truong DQ, Unal G, Arce D, Datta A, Bikson M. Automatic M1‐SO Montage Headgear for Transcranial Direct Current Stimulation (TDCS) Suitable for Home and High‐Throughput In‐Clinic Applications. Neuromodulation. 2018 March 09, doi: 10.1111/ner.12786. PDF
Riggs A, Patel V, Paneri B, Portenoy RK, Bikson M, Knotkova H. At-Home Transcranial Direct Current Stimulation (tDCS) with Telehealth Support for Symptom Control in Chronically-Ill Patients with Multiple Symptoms. Front. Behav. Neurosci. 12:93. 2018 doi: 10.3389/fnbeh.2018.00093. PDF
Chhatbar PY, Kautz SA, Takacs I, Rowland NC, Revuelta GJ, George MS, Bikson M, Feng W. Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo.Brain Stimul. 2018, doi: 10.1016/j.brs.2018.03.006. PDF
Bikson M, Ruiz-Nuño A, Miranda D, Kronberg G, Jiruska P, Fox JE, Jefferys JGR. Synaptic transmission modulates while non-synaptic processes govern the transition from pre-ictal to seizure activity in vitro. bioRxiv 280321. 2018 March 11 doi: 10.1101/280321. PDF
Hee Lee W, Kennedy NI, Bikson M, Frangou S. A computational assessment of target engagement in the treatment of auditory hallucinations with transcranial direct current stimulation. Front. Psychol. 9:48. 2018 Feb 22. doi: 10.3389/fpsyt.2018.00048. PDF
Edemann-Callesen H, Habelt B, Wieske F, Jackson M, Khadka N, Mattei D, Bernhardt N, Heinz A, Liebetanz D, Bikson M, Padberg F, Hadar R, Nitsche MA, Winter C. Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit. Nature Translational Psychiatry. 2018. doi: 10.1038/s41398-017-0059-5. PDF
2017
Bikson M, Brunoni AR, Charvet LE, Clark VP, Cohen LG, Deng Z, Dmochowski J, Edwards DJ, Frohlich F, Kappenman ES, Lim KO, Loo C, Mantovani A, McMullen DP, Parra LC, Pearson M, Richardson JD, Rumsey JM, Sehatpour P, Sommers D, Unal G, Wassermann EM, Woods AJ, Lisanby SH. Rigor and reproducibility in research with transcranial electrical stimulation: An NIMH-sponsored workshop. Brain Stimul. 2017 Dec 29. doi.org/10.1016/j.brs.2017.12.008. PDF
Leite J, Goncalves ÓF, Pereira P, Khadka N, Bikson M, Fregni F, Carvalho S. The differential effects of unihemispheric and bihemispheric tDCS over the inferior frontal gyrus on proactive control. Neurosci Res. 2017. doi.org/10.1016/j.neures.2017.08.005. PDF
Zareen N, Shinozaki M, Ryan D, Alexander H, Amer A, Truong DQ, Khadka N, Sarkar A, Naeem S, Bikson M, Martin JH. Motor cortex and spinal cord neuromodulation promote corticospinal tract axonal outgrowth and motor recovery after cervical contusion spinal cord injury. Exp Neurol. 2017. doi.org/10.1016/j.expneurol.2017.08.004. PDF
Esmaeilpour Z, Marangolo P, Hampstead BM, Bestmann S, Galletta E, Knotkova H, Bikson M. Incomplete evidence that increasing current intensity of tDCS boosts outcomes. Brain Stimul. March-April 2017; 11(2): 310–321 doi: 10.1016/j.brs.2017.12.002. PDF
Meiron O, Gale R, Namestnic J, Bennet-Back O, Davia J, Gebodh N, Adair D, Esmaeilpour Z, Bikson M. High-Definition transcranial direct current stimulation in early onset epileptic encephalopathy: a case study. Brain Inj. 2017 Nov 20. doi: 10.1080/02699052.2017.1390254. PDF
Bikson M, Paneri B, Mourdoukoutas A, Esmaeilpour Z, Badran BW, Azzam R, Adair D, Datta A, Fang XH, Wingeiner B, Chao D, Alonso-Alonso M, Lee K, Knotkova H, Woods AJ, Hagedorn D, Jeffery D, Giordane J, Tyler WJ. Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes and industry standards for wellness, over-the-counter, or prescription devices with low risk. Brain Stimul. 2017 October 15. 11:134-157 doi: 10.1016/j.brs.2017.10.012. PDF
dos Santos MD, Cavenaghi VB, Mac-Kay APMG, Serafim V, Venturi A, Truong DQ, Huang Y, Boggio PS, Fregni F, Simis M, Bikson M, Gagliardi RJ. Non-invasive brain stimulation and computational models in post-stroke aphasic patients: single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial. Sao Paulo Med J. 2017 Nov 6. doi: 10.1590/1516-3180.2016.0194060617. PDF
Rawji V, Ciocca M, Zacharia A, Soares D, Truong D, Bikson M, Rothwell J, Bestmann S. tDCS changes in motor excitability are specific to orientation of current flow. Brain Stimul 2017 Nov 2. doi: 10.1016/j.brs.2017.11.001. PDF
Robinson C, Armenta M, Combs A, Lamphere M, Garza G, Neary J, Wolfe J, Molina E, Semey D, McKee C, Gallegos S, Jones A, Trumbo MC, Al-Azzawi H, Hunter M, lieberman G, Coffman BA, Aboseria M, Bikson M, Clark VP, Witkiewitz K. Modulating affective experience and emotional intelligence with loving kindness meditation and transcranial direct current stimulation: A pilot study. Soc Neurosci, 14:1. 2017. doi:10.1080/17470919.2017.1397054. PDF
Bikson M, Unal G, Brunoni A, Loo C. Special Reports: What psychiatrists need to know about Transcranial Direct Current Stimulation. Psychiatric Times. 2017 Oct 24. PDF
Mourdoukoutas AP, Truong DQ, Adair DK, Simon B, Bikson M. High-Resolution Multi-Scale Computational Model for Non-Invasive Cervical Vagus Nerve Stimulation. Neuromodulation 2017. doi:10.1111/ner/12706. PDF
Shaw MT, Kasschau M, Dobbs B, Pawlak N, Pau W, Sherman K, Bikson M, Datta A, Charvet LE. Remotely Supervised Transcranial Direct Current Stimulation: An Update on Safety and Tolerability. J. Vis. Exp. 2017 Oct7. (128), e56211, doi:10.3791/56211. PDF
Bikson M, Grossman P, Zannou AL, Kronberg G, Truong D, Boggio P, Brunoni AR, Charvet L, Fregni F, Fritsch B, Gillick B, Hamilton RH, Hampstead BM, Kirton A, Knotkova H, Liebetanz D, Liu A, Loo C, Nitsche MA, Reis J, Richardson JD, Rotenberg A, Turkeltaub PE, Woods AJ. Response to letter to the editor : Safety of transcranial direct current stimulation: Evidence based update 2016. Brain Stimul. 2017 Sep-Oct; 10(5): 986-987. doi: https://doi.org/10.1016/j.brs.2017.06.007. PDF
Charvet LE, Dobbs B, Shaw MT , Bikson M, Datta A, Krupp LB. Remotely supervised transcranial direct current stimulation for the treatment of fatigue in multiple sclerosis: Results from a randomized, sham-controlled trial. Mult. Scler. J. 2017 Sep 22; 00(0): 1-10. doi: https://doi.org/10.1177/1352458517732842. PDF
Chrysikou EG, Berryhill ME, Bikson M, Coslett HB. Editorial: Revisiting the Effectiveness of Transcranial Direct Current Brain Stimulation for Cognition: Evidence, Challenges, and Open Questions. Front Hum Neurosci. 2017 Sep 8;11:448. doi: 10.3389/fnhum.2017.00448. PDF
Jackson MP, Bikson M, Liebetanz D, Nitsche M. How to consider animal data in tDCS safety standards. Brain Stimul. 2017 Aug 18. pii: S1935-861X(17)30883-5. doi: 10.1016/j.brs.2017.08.004. PDF
Dmochowski JP, Koessler L, Norcia AM, Bikson M, Parra LC. Optimal use of EEG recordings to target active brain areas with transcranial electrical stimulation. Neuroimage. 2017 Aug 15; 157:69-80. doi: 10.1016/j.neuroimage.2017.05.059. PDF
Chrysikou EG, Berryhill M, Bikson M, Coslett HB. Revisiting the Effectiveness of Transcranial Direct Current Brain Stimulation for Cognition: Evidence, Challenges, and Open Questions. Front. Hum. Neurosci. 2017 Aug. doi: 10.3389/fnhum.2017.00448. PDF
Jackson MP, Truong D, Brownlow ML, Wagner JA, McKinley RA, Bikson M, Jankord R. Safety parameter considerations of anodal transcranial Direct Current Stimulation in rats. Brain Behav Immun. 2017 Aug; 64:152-161. doi: 10.1016/j.bbi.2017.04.008. PDF
Boateng Jr. A, Paneri B, Dufau A, Borges H, Bikson M. Conference proceedings : The effect of cooling electrodes on tDCS tolerability. Brain Stimul. 2017 Jul–Aug ; 10(4): e82–e83. doi: https://doi.org/10.1016/j.brs.2017.04.119. PDF
Esmaeilpour Z, Milosevic M, Azevedo K, Khadka N, Navarro J, Brunoni A, Popovic MR, Bikson M, Fonoff ET. Conference proceedings: Intracranial Voltage Recording During Transcranial Direct Current Stimulation (tDCS) in Human Subjects With Validation of a Standard Model. Brain Stimul. 2017 Jul–Aug; 10(4): e72–e75. doi: https://doi.org/10.1016/j.brs.2017.04.114. PDF
Shaw M, Dobbs B, Pawlak N, Pau W, Sherman K, Bikson M, Datta A, Kasschau M, Frontario A, Charvet L. Conference proceedings: Updated Safety and Tolerability of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS). Brain Stimul. 2017 Jul–Aug; 10(4): e60–e61. doi: https://doi.org/10.1016/j.brs.2017.04.106. PDF
Pawlak N, Agarwal S, Biagioni M, Bikson M, Datta A, Charvet LE. Conference proceedings: Remotely-supervised Transcranial Direct Current Stimulation (RS-tDCS) for Parkinson’s Disease (PD) Clinical Trials: Guidelines and Feasibility. Brain Stimul. 2017 Jul–Aug; 10(4): e59–e60. doi: https://doi.org/10.1016/j.brs.2017.04.105. PDF
Pau W, Shaw M, Dobbs B, Kasschau M, Frontario A, Bikson M, Datta A, Charvet L. Conference proceedings: Mood Improvement with Transcranial Direct Current Stimulation (tDCS) is Specific to Positive vs. Negative Affect in Multiple Sclerosis. Brain Stimul. 2017 July–August ; 10(4): e58–e59. doi: https://doi.org/10.1016/j.brs.2017.04.104. PDF
Dobbs B, Shaw M, Frontario A, Sherman K, Bikson M, Datta A, Kasschau M, Charvet L. Conference proceedings: Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) Improves Fatigue in Multiple Sclerosis. Brain Stimul. 2017 July–August ; 10(4): e57–e58. doi: https://doi.org/10.1016/j.brs.2017.04.103. PDF
Rabau S, Shekhawat GS, Aboseria M, Griepp D, Rompaey VV, Bikson M, de Heyning PV. Comparison of the long-term effect of positioning the cathode in tDCS in tinnitus patients. Front. Aging Neurosci. 2107 Jul 28; 9(217). doi: 10.3389/fnagi.2017.00217. PDF
Chakraborty D, Truong DQ, Bikson M, Kaphzan H. Neuromodulation of axon terminals. Cereb Cortex. 2017 Jun 24:1-9. doi: 10.1093/cercor/bhx158. PDF
Antal A, Alekseichuk I, Bikson M, Brockmöller J, Brunoni AR, Chen R, Cohen LG, Dowthwaite G, Ellrich J, Flöel A, Fregni F, George MS, Hamilton R, Haueisen J, Herrmann CS, Hummel FC, Lefaucheur JP, Liebetanz D, Loo CK, McCaig CD, Miniussi C, Miranda PC, Moliadze V, Nitsche MA, Nowak R, Padberg F, Pascual-Leone A, Poppendieck W, Priori A, Rossi S, Rossini PM, Rothwell J, Rueger MA, Ruffini G, Schellhorn K, Siebner HR, Ugawa Y, Wexler A, Ziemann U, Hallett M, Paulus W. Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. Clin Neurophysiol. 2017 Jun 19. doi:10.1016/j.clinph.2017.06.001. PDF
Rahman A, Lafon B, Parra LC, Bikson M. Direct current stimulation boosts synaptic gain and cooperativity in vitro. J Physiol. 2017 Jun 1;595(11):3535-3547. doi: 10.1113/JP273005. PDF
Dmochowski JP, Bikson M. Noninvasive Neuromodulation Goes Deep. Cell 169, Jun 1, 2017, Elsevier Inc. http://dx.doi.org/10.1016/j.cell.2017.05.017. PDF
De Paolis A, Bikson M, Nelson JT, de Ru JA, Packer M, Cardoso L. Analytical and numerical modeling of the hearing system: advances towards the assessment of hearing damage. Hear Res. 2017 Jun;349:111-128. doi: 10.1016/j.heares.2017.01.015. PDF
Nitsche M. Bikson M. Extending the parameter range for tDCS: Safety and tolerability of 4 mA stimulation. Brain Stimul. 2017 May-Jun; 10( 3): 541-542. doi:https://doi.org/10.1016/j.brs.2017.03.002. PDF
Hampstead BM, Sathian K, Bikson M, Stringer AY. Combined mnemonic strategy training and high-definition transcranial direct current stimulation for memory deficits in mild cognitive impairment. Alzheimers Dement (N Y). 2017 May 15; 3:459-470. doi: 10.1016/j.trci.2017.04.008. PDF
Edwards D, Cortes M, Wortman-Jutt S, Putrino D, Bikson M, Thickbroom G, Pascual-Leone A. Transcranial Direct Current Stimulation and Sports Performance. Front Hum Neurosci. 2017 May 10;11:243. doi: 10.3389/fnhum.2017.00243. PDF
Ezquerro F, Moffa AH, Bikson M, Khadka N, Aparicio LV, Sampaio-Junior B, Fregni F, Bensenor IM, Lotufo PA, Pereira AC, Brunoni AR. The Influence of Skin Redness on Blinding in Transcranial Direct Current Stimulation Studies: A Crossover Trial. Neuromodulation. 2017 Apr;20(3):248-255. doi: 10.1111/ner.12527. PDF
Chen C, Bikson M, Chou L, Shan C, Khadka N, Chen W, Fregn F. Higher-order power harmonics of pulsed electrical stimulation modulates corticospinal contribution of peripheral nerve stimulation. Sci Rep. 2017 Mar 3;7:43619. doi: 10.1038/srep43619. PDF
A. Cancelli, C. Cottone, F. Tecchio, D. Truong, J. Dmochowski, D. Adair, M. Bikson. P094 Method for EEG guided transcranial Electrical Stimulation without models.Clinical Neurophysiology 2017 Mar; 128 (3):e54–e56. doi:10.1016/j.clinph.2016.10.219. PDF
Gebodh N, Adair D, Chelette K, Esmaeilpour Z, Bikson M, Dmochowski J, Parra LC, Woods AJ, Kappenman E. Modulation of physiologic artifacts during concurrent tDCS and EEG. Brain Stimul. 2017 Mar 1;10(2):429-430. doi: http://dx.doi.org/10.1016/j.brs.2017.01.278. PDF
Gebodh N, Adair D, Chelette K, Esmaeilpour Z, Bikson M, Dmochowski J. P128 Physiologic artifacts when combining EEG and tDCS. Clinical Neurophysiology 2017 Mar 1;128(3):e78-e78. doi:10.1016/j.clinph.2016.10.249. PDF
Bai S, Gálvez V, Dokos S, Martin D, Bikson M, Loo C. Computational models of Bitemporal, Bifrontal and Right Unilateral ECT predict differential stimulation of brain regions associated with efficacy and cognitive side effects. Eur Psychiatry. 2017 Mar;41:21-29. doi: 10.1016/j.eurpsy.2016.09.005. PDF
Esmaeilpour Z, Schestatsky P, Bikson M, Brunoni AR, Pellegrinelli A, Piovesan FX, Santos MM, Menezes RB, Fregni F. Notes on Human Trials of Transcranial Direct Current Stimulation between 1960 and 1998. Front Hum Neurosci. 2017 Feb 23;11:71. doi: 10.3389/fnhum.2017.00071. PDF
Charvet L, Shaw M, Dobbs B, Frontario A, Sherman K, Bikson M, Datta A, Krupp L, Zeinapour E, Kasschau M. Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis. Neuromodulation. 2017 Feb 22. doi: 10.1111/ner.12583. PDF
Giordano J, Bikson M, Kappenman ES, Clark VP, Coslett B, Hamblin MR, Hamilton R, Jankord R, Kozumbo WJ, McKinley A, Nitsche MA, Reilly JP, Richardson J, Wurzman R, Calabrese E. Mechanisms and Effects of Transcranial Direct Current Stimulation. Dose Response. 2017 Feb 9;15(1). doi: 10.1177/1559325816685467. PDF
Huang Y*, Liu AA*, Lafon B, Friedman D, Dayan M, Wang X, Bikson M, Doyle WK, Devinsky O, Parra LC, Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation. Elife. 2017 Feb 7;6. doi: 10.7554/eLife.18834. (*authors contributed equally). PDF Summary video
Kronberg G, Bridi M, Abel T, Bikson M, Parra LC. Direct Current Stimulation Modulates LTP and LTD: Activity Dependence and Dendritic Effects. Brain Stimul. 2017 Jan – Feb;10(1):51-58. doi: 10.1016/j.brs.2016.10.001. PDF
Lafon B, Rahman A, Bikson M, Parra LC. Direct Current Stimulation Alters Neuronal Input/Output Function. Brain Stimul. 2017 Jan – Feb;10(1):36-45. doi: 10.1016/j.brs.2016.08.014. PDF
Khadka N, Zannou AL, Zunura F, Truong DQ, Dmochowski J, Bikson M. Minimal heating at the Skin surface during transcranial direct current stimulation (tDCS). Neuromodulation. 2017 Jan 22. doi: 10.1111/ner.12554. PDF
Sebastian R, Saxena S, Tsapkini K, Faria AV, Long C, Wright A, Davis C, Tippett DC, Mourdoukoutas AP, Bikson M, Celnik P, Hillis A. Cerebellar tDCS: A novel approach to augment language treatment post stroke. Front Hum Neurosci. 2017 Jan 12;10:695. doi: 10.3389/fnhum.2016.00695. PDF
De Paolis A, Watanabe H, Nelson JT, Bikson M, Packer M, Cardoso L. Human Cochlear Hydrodynamics: A High-Resolution μCT ImagesBased Finite Element Study. J Biomech. 2017 Jan 4;50:209-216. doi: 10.1016/j.jbiomech.2016.11.020. PDF
2016
Shin DW, Khadka N, Fan J, Bikson M, Fu BM. Transcranial direct current stimulation transiently increases the blood-brain barrier solute permeability in vivo. Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. 2016 Mar 29; 97881X. doi: 10.1117/12.2218197. PDF
Kasschau M, Reisner J, Sherman K, Bikson M, Datta A, Charvet LE. Transcranial Direct Current Stimulation Is Feasible for Remotely Supervised Home Delivery in Multiple Sclerosis. Neuromodulation. 2016 Dec;19(8):824-831. doi: 10.1111/ner.12430. PDF
Jackson MP, Rahman A, Lafon B, Kronberg G, Doris Ling, Parra LC, Bikson M. Animal models of transcranial direct current stimulation: Methods and mechanisms. Clin Neurophysiol. 2016 Nov;127(11):3425-3454. doi: 10.1016/j.clinph.2016.08.016. PDF
Alonzo A, Aaronson S, Bikson M, Husain M, Lisanby S, Martin D, McClintock SM, McDonald WM, O’Reardon J, Esmailpoor Z, Loo C. Study design and methodology for a multicentre, randomised controlled trial of transcranial direct current stimulation as a treatment for unipolar and bipolar depression. Contemp Clin Trials. 2016 Nov;51:65-71. doi: 10.1016/j.cct.2016.10.002. PDF
Teichmann M, Lesoil C, Godard J, Vernet M, Bertrand A, Levy R, Dubois B, Lemoine L, Truong DQ, Bikson M, Kas A, Valero-Cabré A. Direct current stimulation over the anterior temporal areas boosts semantic processing in primary progressive aphasia. Ann Neurol. 2016 Nov;80(5):693-707. doi: 10.1002/ana.24766. PDF
Jog MV, Smith RX, Jann K, Dunn W, Lafon B, Truong D, Wu A, Parra LC, Bikson M, Wang DJ. In-vivo Imaging of Magnetic Fields Induced by Transcranial Direct Current Stimulation (tDCS) in Human Brain using MRI. Sci Rep. 2016 Oct 4;6:34385. doi: 10.1038/srep34385. PDF
Paneri B, Adair D, Thomas C, Khadka N, Patel V, Tyler WJ, Parra L, Bikson M. Tolerability of Repeated Application of Transcranial Electrical Stimulation with Limited Outputs to Healthy Subjects. Brain Stimul. 2016 Sep-Oct;9(5):740-54. doi: 10.1016/j.brs.2016.05.008. PDF
Babyar S, Santos-Pontelli T, Will-Lemos T, Mazin S, Bikson M, Truong D, Edwards D, Reding M. Center of Pressure Speed Changes with tDCS versus GVS in Patients with Lateropulsion after Stroke. Brain Stimul. 2016 Sep-Oct;9(5):796-8. doi: 10.1016/j.brs.2016.06.053. PDF
Bikson M, Grossman P, Thomas C, Zannou AL, Jiang J, Adnan T, Mourdoukoutas AP, Kronberg G, Truong D, Boggio P, Brunoni AR, Charvet L, Fregni F, Fritsch B , Gillick B, Hamilton RH, Hampstead BM, Jankord R, Kirton A, Knotkova H , Liebetanz D, Liu A , Loo C, Nitsche MA, Reis J , Richardson JD , Rotenberg A, Turkeltaub PE, Woods AJ. Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016. Brain Stimul. 2016 Sep-Oct;9(5):641-61. doi: 10.1016/j.brs.2016.06.004. PDF
Hogeveen J, Grafman J, Aboseria M, David A, Bikson M, Hauner KK. Effects of High-Definition and Conventional tDCS on Response inhibition. Brain Stimul. 2016 Sep-Oct;9(5):720-9. doi: 10.1016/j.brs.2016.04.015. PDF
Dmochowski J, Koessler L, Parra LC, Bikson M, Norcia AM. Targeted electrical stimulation of active brain sources using reciprocity. bioRxiv 2016 Sep 30. doi: http://dx.doi.org/10.1101/078758. PDF
Bikson M, Paneri B, Giordano J. The off-label use, utility and potential value of tDCS in the clinical care of particular neuropsychiatric conditions. J Law Biosci. 2016 Sep 10;3(3): 642-646. doi:10.1093/jlb/lsw044. PDF
Cappiello M, Xie W, David A, Bikson M. Zhang W. Transcranial direct current stimulation modulates pattern separation. Neuroreport. 2016 Aug 3;27(11):826-32. doi: 10.1097/WNR.0000000000000621. PDF
Alam M, Truong DQ, Khadka N, Bikson M. Spatial and polarity precision of concentric high-definition transcranial direct current stimulation (HD-tDCS). Phys Med Biol. 2016 Jun 21;61(12):4506-21. doi: 10.1088/0031-9155/61/12/4506. PDF
Cancelli A, Cottone C, Tecchio F, Truong D, Dmochowski J, Bikson M. A simple method for EEG guided transcranial electrical stimulation without models. J Neural Eng. 2016 Jun;13(3):036022. doi: 10.1088/1741-2560/13/3/036022. PDF
Hampstead BM, Briceño EM, Mascaro N, Mourdoukoutas A, Bikson M. Current Status of Transcranial Direct Current Stimulation in Posttraumatic Stress and Other Anxiety Disorders. Curr Behav Neurosci Rep. 2016 Jun;3(2):95-101. doi:10.1007/s40473-016-0070-9. PDF
Dias DR, Trevizol AP, Miorin LA, Bikson M, Aboseria M, Shiozawa P, Cordeiro Q. Effect of Transcranial Direct Current Stimulation Protocol for Treating Depression Among Hemodialysis Patients: A Proof-of-Concept Trial. J ECT. 2016 Jun;32(2):e3-4. doi: 10.1097/YCT.0000000000000273. PDF
Hämmerer D, Bonaiuto J, Klein-Flügge M, Bikson M, Bestmann S. Selective alteration of human value decisions with medial frontal tDCS is predicted by changes in attractor dynamics. Sci Rep. 2016 May 5;6:25160. doi: 10.1038/srep25160. PDF
Santos-Pontelli TE, Rimoli BP, Favoretto DB, Mazin SC, Truong DQ, Leite JP, Pontes-Neto OM, Babyar SR, Reding M, Bikson M, Edwards DJ. Polarity-Dependent Misperception of Subjective Visual Vertical during and after Transcranial Direct Current Stimulation (tDCS). PLoS One. 2016 Mar 31;11(3):e0152331. doi: 10.1371/journal.pone.0152331. PDF
Woods AJ, Antal A, Bikson M, Boggio PS, Brunoni AR, Celnik P, Cohen LG, Fregni F, Herrmann CS, Kappenman ES, Knotkova H, Liebetanz D, Miniussi C, Miranda PC, Paulus W, Priori A, Reato D, Stagg C, Wenderoth N, Nitsche MA. A technical guide to tDCS, and related non-invasive brain stimulation tools. Clin Neurophysiol. 2016 Feb;127(2):1031-48. doi: 10.1016/j.clinph.2015.11.012. PDF
Castillo-Saavedra L, Gebodh N, Bikson M, Diaz-Cruz C, Brandao R, Coutinho L, Truong D, Datta A, Shani-Hershkovich R, Weiss M, Laufer I, Reches A, Peremen Z, Geva A, Parra LC, Fregni F. Clinically Effective Treatment of Fibromyalgia Pain With High-Definition Transcranial Direct Current Stimulation: Phase II Open-Label Dose Optimization. J Pain. 2016 Jan;17(1):14-26. doi: 10.1016/j.jpain.2015.09.009. PDF
2015
Sarantos C, Bekritsky J, Khadka N, Bikson M, Adusumilli P. Design of Wireless Intra-operative pressure sensitive reticulated head (WIPOX2). J Medical Devices. 2015. doi:10.1115/1.4030600. PDF
Rahman A, Lafon B, Bikson M. Multilevel computational models for predicting the cellular effects of noninvasive brain stimulation. Prog Brain Res. 2015;222:25-40. doi: 10.1016/bs.pbr.2015.09.003. PDF
Bikson M, Truong DQ, Mourdoukoutas AP, Aboseria M, Khadka N, Adair D, Rahman A. Modeling sequence and quasi-uniform assumption in computational neurostimulation. Prog Brain Res. 2015;222:1-23. doi: 10.1016/bs.pbr.2015.08.005. PDF
Cancelli A, Cottone C, Parazzini M, Fiocchi S, Truong DQ, Bikson M, Tecchio D. Transcranial Direct Current Stimulation: Personalizing the Neuromodulation. Conf Proc IEEE Eng Med Biol Soc. 2015;2015:234-7. doi: 10.1109/EMBC.2015.7318343. PDF
Knotkova H, Woods AJ, Bikson M, Nitche MA. Transcranial Direct Current Stimulation (tDCS): What Pain Practitioners Need to Know. Practical Pain Management. 2015; 15(3). link
Kasschau M, Sherman K, Haider L, Frontario A, Shaw M, Datta A, Bikson M, Charvet L. A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS). J Vis Exp. 2015 Dec 26;(106):e53542. doi: 10.3791/53542. Video PDF
Donnell A, D Nascimento T, Lawrence M, Gupta V, Zieba T, Truong DQ, Bikson M, Datta A, Bellile E, DaSilva AF. High-Definition and Non-Invasive Brain Modulation of Pain and Motor Dysfunction in Chronic TMD. Brain Stimul. 2015 Nov-Dec;8(6):1085-92. doi: 10.1016/j.brs.2015.06.008. PDF
Galletta EE, Cancelli A, Cottone C, Simonelli I, Tecchio F, Bikson M, Marangolo P. Use of computational modeling to inform tDCS electrode montages for the promotion of language recovery in post-stroke aphasia. Brain Stimul. 2015 Nov-Dec;8(6):1108-15. doi: 10.1016/j.brs.2015.06.018. PDF
Xu J, Healy SM, Truong DQ, Datta A, Bikson M, Potenza MN. A Feasibility Study of Bilateral Anodal Stimulation of the Prefrontal Cortex Using High-Definition Electrodes in Healthy Participants. Yale J Biol Med. 2015 Sep 3;88(3):219-25. PDF
Kurimori M, Shiozawa P, Bikson M, Aboseria M, Cordeiro Q. Targeting negative symptoms in schizophrenia: results from a proof-of-concept trial assessing prefrontal anodic tDCS protocol. Schizophr Res. 2015 Aug;166(1-3):362-3. doi: 10.1016/j.schres.2015.05.029. PDF
DaSilva AF, Truong DQ, DosSantos MF, Toback RL, Datta A, Bikson M. State-of-art neuroanatomical target analysis of high-definition and conventional tDCS montages used for migraine and pain control. Front Neuroanat. 2015 Jul 15;9:89. doi: 10.3389/fnana.2015.00089. PDF
Senco NM, Huang Y, D’Urso G, Parra LC, Bikson M, Mantovani A, Shavitt EG, Hoexter MQ, Miguel EC, Brunoni A. Transcranial direct current stimulation in obsessive–compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes. Expert Rev Med Devices. 2015 Jul;12(4):381-91. doi: 10.1586/17434440.2015.1037832. PDF
Nitsche M, Bikson M, Bestmann S. On the Use of Meta-analysis in Neuromodulatory Non-invasive Brain Stimulation. Brain Stimul. 2015 May-Jun;8(3):666-7. doi: 10.1016/j.brs.2015.03.008. PDF
Seibt O, Brunoni AR, Huang Y, Bikson M. The Pursuit of DLPFC: Non-neuronavigated Methods to Target the Left Dorsolateral Pre-frontal Cortex With Symmetric Bicephalic Transcranial Direct Current Stimulation (tDCS). Brain Stimul. 2015 May-Jun;8(3):590-602. doi: 10.1016/j.brs.2015.01.401. PDF
Brunoni AR, Sampaio-Junior B, Moffa AH, Borrione L, Nogueira BS, Aparício LV, Veronezi B, Moreno M, Fernandes RA, Tavares D, Bueno PV, Seibt O, Bikson M, Fraguas R, Benseñor IM. The Escitalopram versus Electric Current Therapy to treat Depression Clinical Study (ELECT-TDCS): rationale and study design of a non-inferiority, triple-arm, placebo-controlled clinical trial. Sao Paulo Med J. 2015 May-Jun;133(3):252-63. doi: 10.1590/1516-3180.2014.00351712. PDF
Shekhawat GS, Sundram F, Bikson M, Truong D, Ridder DD, Kirk I, Stinear CM, Welch D, Searchfield GD. Intensity, Duration, and Location of High-Definition Transcranial Direct Current Stimulation for Tinnitus Relief. Neurorehabil Neural Repair. 2016 May;30(4):349-59. doi: 10.1177/1545968315595286. PDF
Khadka N, Truong DQ, Bikson M. Principles of Within Electrode Current Steering (WECS). J Med Device 2015 Apr 13-16;9 ,020947-1. doi:10.1115/1.4030126. PDF
Jones KT, Stephens JA, Alam M, Bikson M, Berryhill ME. Longitudinal neurostimulation in older adults improves working memory. PLoS One. 2015 Apr 7;10(4):e0121904. doi: 10.1371/journal.pone.0121904. PDF
Song W, Truong D, Bikson M, Martin JH. Transspinal direct current stimulation immediately modifies motor cortex sensorimotor maps. J Neurophysiol. 2015 Apr 1;113(7):2801-11. doi: 10.1152/jn.00784.2014. PDF
Grecco LH, Li S, Michel S, Castillo-Saavedra L, Mourdoukoutas A, Bikson M, Fregni F. Transcutaneous Spinal Stimulation as a therapeutic strategy for spinal cord injury: State of the art. Journal of Neurorestoratology 2015 March 23;3:73—82. doi: https://doi.org/10.2147/JN.S77813. PDF
Charvet L, Kasschau M, Datta A, Knotkova H, Stevens MC, Alonzo A, Loo C, Krull KR, Bikson M. Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) for Clinical Trials: Guidelines for Technology and Protocols. Front Syst Neurosci. 2015 Mar 17;9:26. doi: 10.3389/fnsys.2015.00026. PDF
Fregni F, Nitsche MA, Loo CK, Brunoni AR, Marangolo P, Leite J, Carvalho S, Bolognini N, Caumo W, Paik NJ, Simis M, Ueda K, Ekhtiari H, Luu P, Tucker DM, Tyler WJ, Brunelin J, Datta A, Juan CH, Venkatasubramanian G, Boggio PM, Bikson M. Regulatory Considerations for the Clinical and Research Use of Transcranial Direct Current Stimulation (tDCS): review and recommendations from an expert panel. Clin Res Regul Aff. 2015 Mar 1;32(1):22-35. doi: 10.3109/10601333.2015.980944. PDF
Reato D, Bikson M. Parra L. Lasting modulation of in-vitro oscillatory activity with weak direct current stimulation. J Neurophysiol. 2015 Mar 1; 113(5):1334-41. doi: 10.1152/jn.00208.2014. PDF
Foerster BR, Nascimento TD, DeBoer M, Bender MA, Rice IC, Truong DQ, Bikson M, Clauw DJ, Zubieta JK, Harris RE, DaSilva AF. Excitatory and inhibitory brain metabolites as targets of motor cortex transcranial direct current stimulation therapy and predictors of its efficacy in fibromyalgia. Arthritis Rheumatol. 2015 Feb;67(2):576-81. doi: 10.1002/art.38945. PDF
Khadka N, Rahman A, Sarantos C, Truong D, Bikson M. Methods for Specific Electrode Resistance Measurement during Transcranial Direct Current Stimulation. Brain Stimul. 2015 Jan-Feb; 8(1):150-9. doi: 10.1016/j.brs.2014.10.004. PDF
Saavedra , Gebodh N, Bikson M, Diaz C, Brandao R, Coutinho L, Shani-Hershkovich R, Weiss M, Laufer I, Reches A, Peremen A, Geva A, Parra LC, Truong D, Fregni F. Clinically Effective Treatment of Fibromyalgia Pain With High-Definition Transcranial Direct Current Stimulation: Phase II Open-Label Dose-Optimization. J Pain. 2016 Jan;17(1):14-26. doi: 10.1016/j.jpain.2015.09.009. PDF
2014
Toshev P, Guleyupoglu B, Bikson M. Informing dose design by modeling transcutaneous spinal direct current stimulation. Clin Neurophysiol. 2014 Nov;125(11):2147-9. doi: 10.1016/j.clinph.2014.03.022. PDF
Gillick BT, Kirton A, Carmel J, Minhas P, Bikson M. Pediatric Stroke and transcranial Direct Current Stimulation: Methods for Rational Individualized Dose Optimization. Front Hum Neurosci. 2014 Sep 19; 8:739. doi: 10.3389/fnhum.2014.00739. PDF
Scheldrup M, Greenwood PM, McKendrick R, Strohl J, Bikson M, Alam A, McKinley RA, Parasuraman R. Transcranial direct current stimulation facilitates cognitive multi-task performance differentially depending on anode location and subtask. Front Hum Neurosci. 2014 Sep 8; 8:665. doi: 10.3389/fnhum.2014.00665. PDF
DosSantos MF, Martikainen LK, Nascimento TD, Love TM, DeBoer MD, Schambra HM, Bikson M, Zubieta J, DaSilva AF. Building up Analgesia in Humans via the Endogenous μ-Opioid System by Combining Placebo and Active tDCS: A Preliminary Report. PLoS One. 2014 Jul 16; 9(7):e102350. doi: 10.1371/journal.pone.0102350. PDF
Richardson JD, Fillmore P, Datta A, Truong D, Bikson M, Fridriksson J. Toward Development of Sham Protocols for High-Definition Transcranial Direct Current Stimulation (HD-tDCS). NeuroRegulation 2014; 1(1) p. 62-72 doi:10.15540/nr.2014.1.1.62. PDF
Guleyupoglu B, Febles N, Minhas P, Hahn C, Bikson M. Reduced discomfort during High-Definition transcutaneous stimulation using 6% benzocaine. Front Neuroeng. 2014 Jul 11;7:28. doi: 10.3389/fneng.2014.00028. PDF
Guarienti F, Caumo W, Shiozawa P, Cordeiro Q, Boggio PS, Benseñor IM, Lotufo PA, Bikson M, Brunoni AR. Reducing transcranial direct current stimulation (tDCS)-induced erythema with skin pretreatment: considerations for sham-controlled tDCS clinical trials. Neuromodulation. 2015 Jun; 18(4):261-5. doi: 10.1111/ner.12230. PDF
Moreno-Duarte I, Gebodh N, Schestatsky P, Guleyupoglu B, Reato D, Bikson M, Fregni F. Transcranial Electrical Stimulation: transcranial Direct Current Stimulation (tDCS), transcranial Alternating Current Stimulation (tACS), transcranial Pulsed Current Stimulation (tPCS), and Transcranial Random Noise Stimulation (tRNS). The Stimulated Brain 2014; (ed. R Cohen Kadosh). Elsevier ISBN 9780124047044, Chapter 2, p.35-60.
Truong D, Minhas P, Nair A, Bikson M. Computational modeling assisted design of optimized and individualized transcranial Direct Current Stimulation protocols . The Stimulated Brain 2014; (ed. R Cohen Kadosh). Elsevier ISBN 9780124047044, Chapter 4, p.85-116.
Antal A, Bikson M, Datta A, Lafon B, Dechent P, Parra LC, Paulus W. Imaging artifacts induced by electrical stimulation during conventional fMRI of the brain. Neuroimage. 2014 Jan 15;85 Pt 3:1040-7. doi: 10.1016/j.neuroimage.2012.10.026. (Cover). PDF
Woods AJ, Hamilton RH, Kranjec A, Minhas P, Bikson M, Yu J, Chatterjee A. Space, Time, and Causality in the Human Brain. Neuroimage. 2014 May 15;92:285-97. doi: 10.1016/j.neuroimage.2014.02.015. PDF
Truong DQ, Huber M, Xie X, Datta A, Rahman A, Parra LC, Dmochowski J, Bikson M. Clinician accessible tools for GUI computational models of transcranial electrical stimulation: BONSAI and SPHERES. Brain Stimul. 2014; 7(4):521-4. doi: 10.1016/j.brs.2014.03.009. PDF Use the free modeling tools here: BONSAI and SPHERES
Schambra HM, Bikson M, Wager TD, DosSantos MF, DaSilva AF. It’s all in your head: reinforcing the placebo response with tDCS. Brain Stimul. 2014 Jul-Aug; 7(4): 623–624. doi: 10.1016/j.brs.2014.04.002. Letter-to-Editor. PDF
Brunoni AR, Shiozawa P, Truong D, Javitt DC, Elkis, H, Fregni F, Bikson M. Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis. Expert Rev Med Devices. 2014 Jul;11(4):383-94. doi: 10.1586/17434440.2014.911082. PDF
Shahid SS, Bikson M, Wen P, Ahfock T. The value and cost of complexity in predictive modelling: role of tissue anisotropic conductivity and fibre tracts in neuromodulation. J Neural Eng. 2014 Jun; 11(3):036002. doi: 10.1088/1741-2560/11/3/036002. PDF
Manuel AL, David AW, Bikson M, Schnider A. Frontal tDCS modulates orbitofrontal reality filtering. Neuroscience. 2014 Apr 18; 265:21-7. doi: 10.1016/j.neuroscience.2014.01.052. PDF
Weiss SA, Bikson M. Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields. Front Hum Neurosci. 2014 Apr 17;8:227. doi: 10.3389/fnhum.2014.00227. PDF Opening editorial to special issue co-edited by M. Bikson and S.H Weiss
Rahman A, Toshev PL, Bikson M. Polarizing cerebellar neurons with transcranial Direct Current Stimulation. Clin Neurophysiol. 2014 Mar; 125(3):435-8. doi: 10.1016/j.clinph.2013.10.003. PDF
Woods AJ, Hamilton R, Kranjec A, Minhaus P, Bikson M, Yu J, Chatterjee A. Exploring structure-function relationships using parallel fMRI and tDCS. Brain Stimul. 2014 Mar- Apr;7(2):e9. doi: http://dx.doi.org/10.1016/j.brs.2014.01.033. PDF
2013
Kessler SK, Woods AJ, Minhas O, Rosen AR, Gorman C, Bikson M. Dosage considerations for transcranial direct current stimulation in children: a computational modeling study. PLOSE ONE In Press 2013, 8(9): e76112. doi:10.1371/journal.pone.0076112. PDF
Bikson M, Bestmann S, Edwards D. Transcranial Devices are not playthings. Nature 2013; correspondence 501:7466. PDF
Guleyupoglu B, Schestatsky P, Edwards D, Fregni F, Bikson M. Classification of methods in transcranial Electrical Stimulation (tES) and evolving strategy from historical approaches to contemporary innovations. Journal of Neuroscience Methods 2013; 219: 291-311. PDF Journal Link
Berker AO, Bikson M, Bestmann S. Predicting the behavioural impact of transcranial direct current stimulation: issues and limitations Frontiers of Human Neuroscience 2013; doi 10.3389/fnhum.2013.00613. PDF
Rahman A, Bikson M. Origins of specificity during tDCS: anatomical, activity-selective, and input-bias mechanisms Frontiers of Human Neuroscience 2013; doi 10.3389/fnhum.2013.00688. PDF
Reato D, Rahman A, Bikson M, Parra LC. Effects of weak transcranial Alternating Current Stimulation on brain activity – a review of known mechanisms from animal studies. Frontiers of Human Neuroscience 2013; doi 10.3389/fnhum.2013.00687. Journal Link PDF
Bikson M, Dmochowski J, Rahman A. The “Quasi-Uniform” Assumption in Animal and Computational Models of Non-Invasive Electrical Stimulation. Brain Stimulation Letter to the Editor 2013; 6:704-705. PDF
Datta A, Zhou X, Su Y, Parra LC, Bikson M. Validation of finite element model of transcranial electrical stimulation using scalp potentials: implications for clinical dose. J Neural Engineering2013;10(3):036018. doi: 10.1088/1741-2560/10/3/036018. PDF
Dmochowski J, Datta A, Huang Y, Richardson JC, Bikson M, Fridriksson J, Parra LC. Targeted Transcranial Direct Current Stimulation for Rehabilitation after Stroke. J Neuroimage 2013; 75:12-19. PDF
Moreno-Duarte I, Morse L, Alam M, Bikson M, Zafonte R, Fregni F. Targeted therapies using electric and magnetic neural stimulation for the treatment of chronic pain in spinal cord injury. Neuroimage2013; 85(3) 1003-1013. PDF
Okano AH, Fontes EB, Montenegro RA, Farinatti PV, Cyrino ES, Min LL, Bikson M, Noakes TD. Brain stimulation modulates the autonomic nervous system, rating of perceived exertion and performance during maximal exercise. British Journal of Sports Medicine 2013. PDF
Cano T, Morales-Quezada JL, Bikson M, Fregni F. Methods to focalize noninvasive electrical brain stimulation: principles and future clinical development for the treatment of pain. Expert Reviews Neurotherapy 2013; 13(5):465-7. PDF
Rahman A, Reato D, Arlotti M, Gasca F, Datta A, Parra LC, Bikson M. Targeted Cellular Effects of Acute Direct Current Stimulation: Somatic and Synaptic Terminal Effects. Journal of Physiology2013; 591.10: 2563-2578. PDF
Truong DQ, Magerowski G, Blackburn GL, Bikson M, Alonso-Alonso M. Computational modeling of transcranial direct current stimulation (tDCS) in obesity: impact of head fat and dose guidelines.Neuroimage Clinical 2013; 2:759-766. PDF
Edwards D, Cortes M, Datta A, Minhas P, Wassermann EM, Bikson M. Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: a basis for high-definition tDCS NeuroImage 2013; 74: 266-275. PDF
Villamar MF, Volz MS, Datta A, Bikson N, DaSilva AF, Fregni F. Technique and Considerations in the Use of 4×1 Ring High-definition Transcranial Direct Current Stimulation (HD-tDCS). JOVE 2013; (77) doi: 10.3791/50309. WATCH
Chrysikou EG, Hamilton RH, Coslett HB, Datta A, Bikson N, Thompson-Schill SL. Non-invasive transcranial direct current stimulation over the left prefrontal cortex facilitates cognitive flexibility in tool use. Cognitive Neuroscience 2013; 4(2) 81-89. TEXT
Villamar MF, Wivatvongvana P, Patumanond J, Bikson M, Truong DQ, Datta A, Fregi F. Focal modulation of primary motor cortex in Fibromyalgia using 4×1-Ring High-Definition Transcranial Direct Current Stimulation (HD-tDCS): Immediate and delayed analgesic effects of cathodal and anodal stimulation. J Pain 2013; 14(4): 371-83. PDF
Reato D, Gasca F, Datta, A, Bikson M, Marshall L, Parra LC. Transcranial electrical stimulation accelerates human sleep homeostasis. PLOS Computational Biology 2013; 9(2): e1002898. doi:10.1371/journal.pcbi.1002898. LINK
Hahn C, Rice J, Macuff S, Minhas P, Rahman A, Bikson M. Methods for extra-low voltage transcranial Direct Current Stimulation: Current and time dependent impedance decreases. Clinical Neurophysiology 2013; 124(3) 551-556. PDF
Datta A, Dmochowski J, Guleyupoglu B, Bikson M, Fregni F. Cranial Electrotherapy Stimulation and transcranial Pulsed Current Stimulation: A computer based high-resolution modeling studyNeuroimage 2013; 65:280-287. PDF
Kuo HI, Datta A, Bikson M, Minhas P. Paulus W, Kuo MF, Nitsche MA. Comparing cortical plasticity induced by conventional and high-definition 4×1 ring tDCS: a neurophysiological study Brain Stimulation 2013; 6(4):644-8. PDF Journal Link
Weiss SA, McKhann G, Goodman R, Emerson RG, Trevelyan A, Bikson M, Schevon CA. Field effects and ictal synchonization: insights from in homine observations Frontiers of Human Neuroscience2013; 7:828. PDF
2012
Datta A, Troung D, Minhas P, Parra LC, Bikson M. Inter-individual variation during transcranial Direct Current Stimulation and normalization of dose using MRI-derived computational models.Frontiers in Neuropsychiatric Imaging and Stimulation. 2012; 3:91. doi: 10.3389/fpsyt.2012.00091. PDF
Bikson M, Rahman A, Datta A. Computational Models of Transcranial Direct Current Stimulation.Clinical EEG and Neuroscience . 2012; 43(3) 176-183. PDF
Dasilva AF, Mendonca ME, Zaghi S, Lopes M, Dossantos MF, Spierings EL, Bajwa Z, Datta A, Bikson M, Fregni F. tDCS-Induced Analgesia and Electrical Fields in Pain-Related Neural Networks in Chronic Migraine. Headache. 2012; 52(8) 1283-95. PDF
Medina J, Beauvais J, Datta A, Bikson M, Coslett HB, Hamilton RH. Transcranial direct current stimulation accelerates allocentric target detection. Brain Stimulation. 2012; 6(3) 433-9. PDF Journal Link
Dmochowski JP, Bikson M, Parra LC. The point spread function of the human head and its implications for transcranial current stimulation. Phys Med Biol. 2012; 57(20) 6459-77. PDF
Kronberg G, Bikson M. Electrode assembly design for transcranial Direct Current Stimulation: A FEM modeling study. Conf Proc IEEE Eng Med Biol Soc. 2012; 891-5. doi: 10.1109/EMBC.2012.6346075. PDF
Truong DQ, Magerowski G, Pascual-Leone A, Alonso-Alonso M, Bikson M. Finite Element Study of Skin and Fat Delineation in an Obese Subject for Transcranial Direct Current Stimulation. Conf Proc IEEE Eng Med Biol Soc. 2012; 6587-90. doi: 10.1109/EMBC.2012.6347504. PDF
Truong DQ, Datta A, Xu J, Fregni F, Bikson M. Optimization of Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling studying. Conf Proc IEEE Eng Med Biol Soc. 2012; Slides: PDF
Minhas P, Bikson M, Woods A, Rosen A, Kessler S. Transcranial Direct Current Stimulation in Pediatric Brain: A computational modeling study. 859-62. doi: 10.1109/EMBC.2012.6346067. Conf Proc IEEE Eng Med Biol Soc. 2012. PDF Free PMIC
Arlotti M, Rahman A, Minhas P, Bikson M. Axon terminal polarization induced by weak uniform DC electric fields: a modeling study. Conf Proc IEEE Eng Med Biol Soc. 2012; 4575-8. doi: 10.1109/EMBC.2012.6346985. PDF
Dmochowski J, Bikson M, Datta A, Richardson J, Fridriksson J, Parra L. On the Role of Electric Field Orientation in Optimal Design of Transcranial Electrical Stimulation Conf Proc IEEE Eng Med Biol Soc. 2012; 6426-9. doi: 10.1109/EMBC.2012.6347465. PDF
Caparelli-Daquer E, Zimmermann TJ, Mooshagian E, Parra L, Rice J, Datta A, Bikson M, Wassermann EA. Pilot Study on Effects of 4×1 High-Definition tDCS on Motor Cortex Excitability.Conf Proc IEEE Eng Med Biol Soc. 2012; 735-8. doi: 10.1109/EMBC.2012.6346036. PDF
Bikson M, Rahman A, Datta A, Fregni F, Merabet L. High-Resolution Modeling Assisted Design of Customized and Individualized Transcranial Direct Current Stimulation Protocols. Neuromodulation: Technology at the Neural Interface. 2012; 15:306-315. PDF
Elwassif MM, Datta A, Rahman A, Bikson M. Temperature control at DBS electrodes using a heat sink: experimentally validated FEM model of DBS lead architecture. Journal of Neural Engineering . 2012; 8(4). PDF
Borckardt JJ, Bikson M, Frohman H, Reeves ST, Datta A, Bansal V, Madan A, Barth K, George MS. A Pilot Study of the Tolerability and Effects of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Pain Perception. Journal of Pain . 2012; 13(2): 112-120. PDF
Peterchev AV, Wagner TM, Miranda PC, Nitsche MA, Paulus W, Lisanby SG, Pascual-Leone A, Bikson M. Fundamentals of transcranial electric and magnetic stimulation dose: definition, selection, and reporting practices. Brain Stimulation 2012; 5:435-53. PDF
Bikson M, Reato D, Rahman A. Cellular effects of electric and magnetic fields: insights animal models and in slice. In Transcranial Brain Stimulation (Frontiers in Neuroscience) 2012 ed. Carolo Miniussi, Walter Paulus, Paolo M. Rossini. CRC Press. ISBN 978-1439875704 p55-92. PDF
Bikson M, Datta A. Guidlines for precise and accurate models of tDCS. Brain Stimulation 2012; 5:430-4. PDF
Brunoni AR, Nitsche MA, Bolognini N, Bikson M et al. Clinical research with transcranial direct current stimulation (tDCS): Challenges and Future Directions. Brain Stimulation 2012; 5(3): 175-95. PDF
2011
Dasilva AF, Volz MS, Bikson M, Fregni F. Electrode positioning and montage in transcranial direct current stimulation. JOVE . 2011; (51). Video
Turkeltaub PE, Benson J, Hamilton RH, Datta A, Bikson M, Coslett HB. Left lateralizing transcranial direct current improves reading efficiency. Brain Stimulation 2011; 5:201-7. PDF
Dmochowski JP, Datta A, Bikson M, Su Y, Parra LC. Optimized multi-electrode stimulation increases focality and intensity at target. Journal of Neural Engineering . 2011; 8(4). PDF
Datta A, Baker J, Bikson M, Fridriksson F. Individualized model predicts brain current flow during transcranial direct-current stimulation treatment in responsive stroke patient. Brain Stimulation2011; 4: 169-74. PDF PubMed HTML
Halko M, Datta A, Plow E, Scaturro J, Bikson M, Merabet L. Neuroplastic changes following rehabilitative training correlate with regional electrical field induced with tDCS. NeuroImage . 2011; 57: 885-891. PDF
Mendonca ME, Santana MB, Baptista AF, Datta A, Bikson M, Fregni D, Araujo CP. Transcranial DC Stimulation in Fibromyalgia: Optimized cortical target supported by high-resolution computational models. Journal of Pain . 2011; 12(5):610-617. PDF
Minhas P, Datta A, Bikson M. Cutaneous perception during tDCS: Role of electrode shape and sponge salinity. Clinical Neurophysiology. 2011; 122:637-638. PDF
Bikson M, Datta A, Elwassif M, Bansal V, Peterchev AV. Introduction to Electrotherapy Technology. in Brain Stimulation in the Treatment of Pain. ed. Helena Knotkova, Ricardo Crucianim, and Joav Merrick. Nova Science, New York 2011 ISBN 978-1-60876-690-1. PDF
J. P. Dmochowski, M. Bikson, A. Datta, Y. Su and L. C. Parra, “A multiple electrode scheme for optimal non-invasive electrical stimulation,” Neural Engineering (NER), 2011 5th International IEEE/EMBS Conference on, Cancun, 2011, pp. 29-35. doi: 10.1109/NER.2011.5910482. PDF
2010
Reato D, Rahman A, Bikson M, Parra L. Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing. Journal of Neuroscience. 2010; 30(45):15067-79. PDF
Servais EL, Rizk NP, McGwyver LO, Rusch VW, Bikson M, Adusumilli PS. Real-time intraoperative detection of tissue hypoxia in gastrointestinal surgery by Wireless Pulse Oximetry (WiPOX). Surgical Endoscopy. 2010; 25(5):1383-9. PDF
Datta A, Rahman A, Scaturro J, Bikson M. Electrode montages for tDCS and weak transcranial electrical stimulation Role of “return” electrode’s position and size. Clinical Neurophysiology. 2010; 121:1976-1978. PDF
Minhas P, Patel J, Bansal V, , Ho J, Datta A, Bikson M. Electrodes for high-definition transcutaneous DC stimulation for applications in drug-delivery and electrotherapy, including tDCS. Journal of Neuroscience Methods . 2010; 190(2):188-97. PDF
Datta A, Bikson M, Fregni F. Transcranial direct current stimulation in patients with skull defects and skull plates: High-resolution computational FEM study of factors altering cortical current flow.Neuroimage . 2010; 52(4):1268-78. PDF
Sunderam S, Gluckman B, Reato D, Bikson M. Toward rational design of electrical stimulation strategies for epilepsy control. Epilepsy & Behavior. 2010; 17:6-22. PDF
Lopez-Quitero SV, Datta A, Amaya R, Elwassif M, Bikson M, Tarbell JM. DBS-relevant electric fields increase hydraulic conductivity of in vitro endothelial monolayers. Journal of Neural Engineering . 2010; 7(1). PDF
2009
Radman T, Ramos RL, Brumberg JC, Bikson M. Role of cortical cell type and morphology in sub- and suprathreshold uniform electric field stimulation. Brain Stimulation. 2009; 2(4):215-228. PDF
Datta A, Bansal V, Diaz J, Patel J, Reato D, Bikson M. Gyri –precise head model of transcranial DC stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad.Brain Stimulation. 2009; 2(4):201-207. PDF
Datta A, Elwassif M. Bikson M. Establishing safety limits for transcranial direct current stimulationClinical Neurophysiology . 2009; 120:1033-1034. PDF
Bikson M, Datta A, Elwassif M. Bio-heat transfer model of transcranial DC stimulation: Comparison of conventional pad versus ring electrode IEEE EMBS. 2009. PDF
2008
Bikson M, Bulow P, Stiller JW, Datta A, Battaglia F, Karnup SV, Postolache TT. Transcranial direct current stimulation for major depression: a general system for quantifying transcranial electrotherapy dosage. Current Treatment Options in Neurology. 2008; 10:377-85. PDF
Datta A, Elwassif M, Battaglia F, Bikson M. Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis. Journal of Neural Engineering. 2008; 5:163-174. PDF
An JH, Radman T, Su Y, Bikson M. Effects of glucose and glutamine concentration in the formulation of the artificial cerebrospinal fluid (ACSF). Brain Research. 2008; 1218:1586-93. PDF
Su Y, Radman T, Vaynshteyn J, Parra LC, Bikson M. Effects of high-frequency stimulation on epileptiform activity in vitro: ON/OFF control paradigm. Epilepsia. 2008; 49:1586-93. PDF
2007
Radman T, Su Y, An JH, Parra L, Bikson M. Spike timing amplifies the effect of electric fields on neurons: Implications for endogenous field effects Journal of Neuroscience. 2007; 27:3030-3036. PDF
Fox JE, Bikson M, Jefferys JG. The effect of neuronal population size on the development of epileptiform discharges in the low calcium model of epilepsy. Neuroscience Letters. 2007; 411:158-61. PDF
1999-2006
Elwassif MM, Kong Q, Vazquez M, Bikson M. Bio-heat transfer model of deep brain stimulation-induced temperature changes. Journal of Neural Engineering. 2006; 3:306-15. PDF
Merrill D, Bikson M, Jefferys JGR. Electrical stimulation of excitable tissue: design of efficacious and safe protocols. Journal of Neuroscience Methods. 2005; 141: 171-198. PDF
Fox JE, Bikson M, Jefferys JGR. Tissue resistance changes and the profile of synchronized neuronal activity during ictal events in the low calcium model of epilepsy. Journal of Neurophysiology. 2004; 92: 181-188. PDF
Bikson M, Inoue M, Akiyama H, Deans JK, Fox JE, Miyakawa H, Jefferys JGR. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. Journal of Physiology. 2004; 557: 175-190. PDF
Durand DM, Bikson M. Control of neuronal activity by electric fields: in-vitro models of epilepsy. In .Deep Brain Stimulation. 2003; Hans Luders ed. Martin Dunitz Ltd. ISBN 978-1841842592. PDF
Bikson M, Hahn PJ, Fox JE, Jefferys JGR. Depolarization block of neurons during maintenance of electrographic seizures. Journal of Neurophysiology. 2003; 90: 2402-2408. PDF
Jefferys JGR, Deans J, Bikson M, Fox J. Effects of weak electric fields on the activity of neurons and neuronal network. Radiation Protection Dosimetry. 2003; 106:321-323. PDF
Shuai J, Bikson M, Lian J, Hahn PJ, Durand DM. Ionic mechanisms underlying spontaneous CA1 neuronal firing in Ca2+-Free Solution. Biophysical Journal 2003; 84: 2099-111. PDF
Lian J, Bikson M, Sciortino C, Stacey WC, Durand DM. Local suppression of epileptiform activity by AC Fields. Journal of Physiology. 2003; 547: 427-434. PDF
Bikson M, Fox JE, Jefferys JGR. Neuronal aggregate formation underlies spatio-temporal dynamics of non-synaptic seizure initiation. Journal of Neurophysiology. 2003; 89: 2330-2331. PDF
Bikson M, Id Bihi R, Vreugdenhil M, Kohling R, Fox JE, Jefferys JGR. Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro. Neuroscience 2002; 115: 253-263. PDF
Lian J, Bikson M, Shuai J, Durand DM. Propagation of non-synaptic epileptiform activity across lesion in rat hippocampal slices. Journal of Physiology 2001; 537; 191-199. PDF
Bikson M, Baraban SC, Durand DM. Conditions sufficient for non-synaptic epileptogenesis in the CA1 region of rat hippocampal slices. Journal of Neurophysiology 2001; 87:62-71. PDF
Bikson M, Lian J, Hahn PJ, Stacey WC, Sciortino C, Durand DM. Suppression of epileptiform activity by high frequency sinusoidal fields in rat hippocampal slices. Journal of Physiology 2001; 531:181-191. PDF
Durand DM, Bikson M. Suppression and control of epileptiform activity by electrical stimulation: a review. Proceedings of the IEEE 2001; 89:1065-1082. PDF
Ghai R, Bikson M, Durand DM. Effects of applied electric fields on low calcium epileptiform activity in the CA1 region of rat hippocampal slices. Journal of Neurophysiology 2000; 84:274-280. PDF
Bikson M, Ghai R, Baraban SC, Durand DM. Modulation of burst frequency, duration, and amplitude in the zero-Ca+2 model of epileptiform activity. Journal of Neurophysiology 1999; 82:2262-70. PDF
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2014 FrenchTV “Electrodes for a Better Brain” video in french May 20, 2014
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Runner’s World “Zap Your Brain to Run Faster” link Feb 27, 2013
2012 “Electrical brain stimulation gains ground” San Fransico Chronicle; Oct 30, 2012 link
2012 “tDCS Course” at Harvard Medical School Lecture on “tDCS Dose and Mechanism.” Watch the talk- Low Res Version Only or on YouTube